Erythema induratum of bazin eib is considered a tuberculide reaction and consists of recurrent painful nodules predominantly on the calves. Erythema induratum of bazin which occurred after tumor necrosis factor antagonist therapy. Erythema induratum is a panniculitis on the calves. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of tuberculid occurring on the legs, whereas nodular vasculitis represents the nontuberculous counterpart. It is considered to be a hypersensitivity response to mycobacterium tuberculosis. Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosis, and it was formerly thought to be always a reaction to the tuberculum bacillus.
A purified protein derivative and quantiferon test were positive, favoring the diagnosis of erythema induratum of bazin. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower legs that, histopathologically, show a lobular panniculitis. Erythema of bazin patient with endometrial tuberculosis. Epidemiological, clinical and laboratorial profile of 54 patients. Erythema induratum of bazin is a rare disease, characterized by the appearance of cutaneous erythema tous nodules, sometimes painful with frequent.
Treatment with a standard fourdrug antituberculous regimen resulted in radiographic and clinical improvement. S254 posters miscellaneous i p291 erythema induratum of bazin s. Erythema induratum of bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women. Erythema induratum an overview sciencedirect topics.
As mentioned earlier the term erythema induratum of bazin is usually reserved for cases of erythema induratum with a tuberculous causation. Erythema induratum of bazin eib is considered to be a tuberculid. The medical eponym bazin disease was historically synonymous, but it applies only to the tuberculous form and is dated. Changes in cortisol metabolism following rifampicin therapy.
The egitema study reported the clinical case of a patient with eib who, after tuberculosis treatment, evolved with adrenal insufficiency. Erythema induratum of bazin associated with addisons. The trip database provides clinical publications about evidence. A biopsy revealed changes consistent with nodular vasculitis.
However, the true origin of the disease is a subject of speculation and remains. It occurs mainly in women, but it is very rare defined pathogen. The term erythema induratum of bazin is usually reserved for. The egitema study reported the clinical case of a patient with eib who, after tuberculosis treatment, evolved with. This report documents the cases of two patients with ulcerating leg nodules. Hidden tuberculous lymphadenitis and miliary tuberculosis in an erythema induratum patient. Vasculitis and zones of fat necrosis are absent in en and frequent in erythema induratum. Tuberculin skin tests are strongly positive in most cases. The term erythema induratum of bazin refers to the tuberculosisassociated lesions, and. Successful treatment of erythema induratum of bazin following. Erythema induratum of bazin is a rare entity, the cause and treatment of which are topics of continuing controversy. Pdf erythema induratum of bazin eib is a tuberculid showing lobular panniculitis. Erythema induratum of bazin associated with addisons disease. Pdf erythema induratum of bazin tuberculosis in disguise.
Receive free email alerts when new articles cite this. A clinical and histopathological profile of patients with cutaneous tuberculosis. Home journals european journal of dermatology disseminated erythema induratum of bazin. The existence of cutaneous nodules makes it necessary to perform a differential diagnosis between different clinical entities. Erythema induratum of bazin is a rare disease, characterized by the appearance of cutaneous erythema tous nodules, sometimes painful with frequent evolution to ulceration. Erythema induratum of bazin eib is considered to be a tuberculid reaction and consists of recurrent painful nodules. Erythema induratum of bazin in a patient with endometrial tuberculosis. Erythema induratum of bazin in a patient with postgraduate. Clinically it has common features with diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. Erythema nodosum must be distinguished from erythema induratum and nodular vasculitis. In patients suspected to have en but with necrotizing vasculitis, the possibility of cutaneous polyarteritis nodosa must be. Erythema induratum of bazin, nodular vasculitis histr. Erythema induratum is a rare granulomatous lobular panniculitis that most commonly affects women in their 40s.
Erythema induratum was first identified in 1861, by bazin, as a nodular eruption that occurred on the lower legs posterior face of young women with tuberculosis. Erythema induratum of bazin eib nodular vasculitis associated with mycobacterium tuberculosis tb and tuberculosisassociated ocular inflammation tbaoi represent uncommon manifestations of tb. There has been a long controversy about the tuberculous cause of erythema induratum, a chronic form of nodular vasculitis. We present a rare case of disseminated eib, in which igra was negative and. Ideal sources for wikipedia s health content are defined in the guideline wikipedia. What are the differential diagnoses for erythema induratum. Erythema induratum definition of erythema induratum by. Pdf an 81yearold woman with a history of renal cell carcinoma and years. Erythema induratum ei was first described by bazin in 1861, who attributed the condition to tuberculosis tb.
In 1945, montgomery et al, while fully acknowledging the existence of tuberculosisassociated erythema induratum, coined the term nodular vasculitis to describe chronic inflammatory nodules of the legs that s. We studied 101 skin biopsy specimens from 86 patients with clinicopathologic diagnosis of erythema induratum of bazin. Mobus bazin, nodularvaskulitis, nodulare vaskulitis, nodoses tuberkulid, subakute, nodulare, migratorische panniculitis villanova at. Erythema induratum of bazin eib nodular vasculitis associated with mycobacterium tuberculosis tb and tuberculosisassociated ocular. Vermutet wird eine hyperergische reaktion gegen mycobacterium tuberculosis. Poncets disease is a reactive arthritis that may accompany tuberculosis. Eritema induratum bazin pdf we describe two cases of erythema induratum of bazin eib, a cutaneous form of tb. Erythema induratum of bazin, a chronic form of nodular vasculitis, may be associated with chronic infections by mycobacterium tuberculosis. The term erythema induratum of bazin refers to the tuberculosisassociated lesions, and erythema induratum of whitfield refers to lesions that are nontuberculous. There is limited data and a lack of diagnostic and treatment standards for these conditions. John libbey eurotext european journal of dermatology.
Erythema induratum oe bazin, international journal of. The case of a female patient from the city of santa marta colombia with recurrent skin abscesses. It is considered to be a hypersensitivity reaction to m. Disseminated erythema induratum of bazin springerlink. In 1861, bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis. Erythema induratum is an indolent eruption of illdefined nod ules affecting the backs of the lower legs of young or middle aged women.
From the departments of dermatology at hospital del mar. Computed tomography showed bilateral enlargement of the adrenal glands, with preserved outlines. Bazin 18071878, paris, erstbeschreibung im jahre 1861 syn. It occurs mainly in women, but it is very rare now. Cases had no signs of active tb, but had a positive interferon. Successful treatment of erythema induratum of bazin. Erythema induratum also referred to as erythema induratum of bazin eib or nodular vasculitis is a chronic nodular skin disease that is thought to represent a.
Erythema induratum of bazin is a hypersensitivity reaction to the tubercle bacillus. Erythema induratum of bazin eib is a tuberculid, a condition occurring on the legs of female. Baba n, takashima w, tokuriki a, ameshima s, hasegawa m. Get a printable copy pdf file of the complete article 318k, or click on a page image below to browse page by page.